"How to get rid of dust mites" Reducing dust mites in your home can alleviate allergies and improve air quality. Wash bedding regularly in hot water to kill mites and their eggs. Use allergen-proof covers for mattresses, pillows, and duvets. Vacuum carpets and upholstery frequently, preferably with a HEPA-filtered vacuum cleaner. Dust surfaces with a damp cloth instead of dry dusting. Keep humidity levels below 50% using a dehumidifier, and avoid clutter that can accumulate dust. If allergies persist, consider consulting with an allergist for additional advice and treatment options.